Pharmacology: capsule possess hepatoprotective and antioxidant activity.
The hepatoprotective effect is due to stimulation of synthesis of
structural and functional proteins and phospholipids, as well as
acceleration of the regeneration of hepatocytes.
Antioxidant effect is determined by interaction of bioflavones with free
radicals in the liver and its detoxication. In such manner the process of
peroxidation of the lipids is interupted and further liver destruction is
Clinically, these effects are manifested by improvement of the signs
and symptoms and normalization of the liver variables (serum level of
transaminases, gamma-globulins, and bilirubin). Dosage & administration:
One Silybin 140 mg capsule should be taken 3 times daily as per the instruction of a physician. The medication should be continued until the relief of the symptoms according to the advice of physician.
A mild laxative effect has occasionally been observed.
No adequate data of investigations are available about the use of this
drug in children. Therefore, it should be used in children under 12
years of age with caution under the direct supervision of a physician. Pregnancy and Lactation:
No experience is available about the use of Silymarin 70 mg or 140
mg during pregnancy and lactation. Therefore, if needed Silymarin 70
mg or 140 mg should be taken with caution according to the physician’s advice.
To be stored in a cool and dry place, away from direct sunlight. Keep
the medicine out of reach of children.